Dec 19, 2018

  • Updated the DepMap Public 18Q4 README to version 2.

Nov 9, 2018

  • Corrected the expression data to fix incorrect gene symbols for some genes. See the corrected dataset here.

November 5, 2018

New data and summary overviews

  • Expression data now TPM instead of RPKM

  • New mutation categories, see here for details

August 31, 2018

Correction to 18Q1, 18Q2 and 18Q3 copy number datasets.

  • 18Q1, 18Q2 and 18Q3 copy number datasets have been updated to correctly reflect released cell lines. These updated files are named "public_18Q3_gene_cn_v2.csv" and so on.

August 6, 2018

More data, new apps, and a new way to get an overview.

  • New 18Q3 Avana + Omics DepMap Release

  • All RNAi data is now processed by DEMETER2

  • New downloads section includes all data from Achilles and CCLE portals

  • New gene overview provides at-a-glance results for a gene (and works on mobile!)

  • New Cell STRAINER app allows users to assess genetic discordance between their cell line sample to the corresponding reference in CCLE

May 7, 2018

Updated DepMap data to "Public 18Q2" Release

  • Avana CRISPR screen dataset expanded to include 436 cell lines.

  • Mutation, indel, copy number and gene expression data also expanded to include new lines in Avana dataset

  • Added Combined Broad, Novartis, Marcotte et al. RNAi data: 713 unique cell lines screened across three large-scale RNAi datasets, with integrated gene dependencies estimated using the DEMETER2 algorithm

June 6, 2018

  • Corrected incorrect copy number data which was shown for some cell lines.