LS513

Depmap ID: ACH-000007

CCLE Name: LS513_LARGE_INTESTINE

COSMIC ID: 907795

Sanger ID: 569

Disease

Colon/Colorectal Cancer

Disease Subtype

Colon Carcinoma

Lineage

Colorectal

Primary/Metastasis

Primary

Source

ATCC

Gender

Male

LS513 sequenced and profiled in following datasets

Loss-of-function screens

CRISPR (Avana) Public 19Q3
CRISPR (Sanger)
Combined RNAi (Broad, Novartis, Marcotte)
RNAi (Broad)
RNAi (Novartis)

Omics Characterizations

Expression Public 19Q3
Copy Number Public 19Q3
Mutation Public 19Q3
Fusion 19Q3
Translocation
Protein Array
Methylation (1kb upstream TSS)
Copy Number (Absolute)

Compound Viability screens

Drug sensitivity AUC (Sanger)
Drug sensitivity IC50 (Sanger)
Drug sensitivity AUC (CTD^2)
Drug sensitivity (PRISM Repurposing Primary Screen) 19Q3
Drug sensitivity replicate-level dose (CTD^2)

Top 10 preferentially essential genes

CRISPR (Avana) Public 19Q3

FAM126B
KLF5
MARK2
DACH1
KRAS
IQGAP1
CDX2
SKI
RAB10
RAF1

Combined RNAi (Broad, Novartis, Marcotte)

KRAS
CTNNB1
BCL2L1
HSPA8
TFRC
GINS2
KIF11
USP7
NOL11
TOP1

Mutation

Loading table...

Fusion

Loading table...

Translocation

Loading table...