KPNYN

Depmap ID: ACH-000227
CCLE Name: KPNYN_AUTONOMIC_GANGLIA
COSMIC ID: 907314
Sanger ID: 1977
Cellosaurus RRID: CVCL_1341
Aliases: KP-N-YN
Disease
Neuroblastoma

Lineage Subtype

Neuroblastoma

Lineage Sub-subtype

MYCN Amp
Primary/Metastasis
Metastasis

KPNYN sequenced and profiled in following datasets


Top 10 preferentially essential genes
CRISPR (Avana) Public 20Q1

ISL1
CHMP4B
TFAP2B
ABCB7
ORC6
CHEK1
GLRX3
NFS1
PCM1
LYRM4
Combined RNAi (Broad, Novartis, Marcotte)

RPA1
CLSPN
EIF4A3
CDK11B
HSPA8
SF3B2
ORC1
POLR2A
SF3B6
SUPT6H



Mutation

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Fusion

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STR Profile

Notation STR matches public reference profile
D3S1358 15, 17
TH01 7, 9
D21S11 28, 29
D18S51 14
Penta E 16, 18
D5S818 10, 11
D13S317 8, 11
D7S820 11, 13
D16S539 12
CSF1PO 10, 12
Penta D 12, 13
vWA 14, 17
D8S1179 12, 13
TPOX 8, 11
FGA 22, 23
AMEL X, Y
Mouse Negative