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K562

Depmap ID: ACH-000551
CCLE Name: K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
COSMIC ID: 905940
Sanger ID: 2098
Cell Line Passport: SIDM00791
Cellosaurus RRID: CVCL_0004
Aliases: K-562
Disease
Leukemia

Disease Subtype

Chronic Myelogenous Leukemia (CML), blast crisis
Lineage
Blood

Lineage Subtype

CML

Lineage Sub-subtype

Blast Crisis
Primary/Metastasis
Metastasis

K562 sequenced and profiled in following datasets


Top 10 preferentially essential genes
CRISPR (DepMap 21Q4 Public+Score, Chronos)

SMCHD1
MPPE1
SOS1
MYB
UBE2S
GAB2
YPEL1
SLC9B1
LMO2
BCR
RNAi (Achilles+DRIVE+Marcotte, DEMETER2)

PTPN1
B4GALT4
ABL1
IL1RL1
MTHFD1
ECD
SCD
RBBP4
POLRMT
HIF3A



Mutation

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