HOP62

Depmap ID: ACH-000861
CCLE Name: HOP62_LUNG
COSMIC ID: 905972
Sanger ID: 1500
Cellosaurus RRID: CVCL_1285
Aliases: HOP-62
Disease
Lung Cancer

Disease Subtype

Non-Small Cell Lung Cancer (NSCLC), Adenocarcinoma
Lineage
Lung

Lineage Subtype

NSCLC

Lineage Sub-subtype

NSCLC Adenocarcinoma
Primary/Metastasis
Primary

HOP62 sequenced and profiled in following datasets

Loss-of-function screens

CRISPR (Avana) Public 20Q4
CRISPR (Sanger)
Combined RNAi (Broad, Novartis, Marcotte)
RNAi (Broad)

Omics Characterizations

Expression Public 20Q4
Copy Number Public 20Q4
Mutation Public 20Q4
Protein Array

Compound Viability screens

Drug sensitivity AUC (Sanger GDSC1)
Drug sensitivity AUC (Sanger GDSC2)
Drug sensitivity IC50 (Sanger GDSC1)
Drug sensitivity IC50 (Sanger GDSC2)
Drug sensitivity replicate-level dose (Sanger GDSC1)
Drug sensitivity replicate-level dose (Sanger GDSC2)
Top 10 preferentially essential genes
CRISPR (Avana) Public 20Q4

FBXO42
ELMO2
TSC22D2
PHLDB3
KRAS
PSMG1
VPS4A
FERMT2
FXN
SCAP
Combined RNAi (Broad, Novartis, Marcotte)

IARS2
KRAS
FOXO1
IL6R
OPA1
THNSL2
RHOA
OR4K17
DNAJC11
PANK3


Mutation

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