OVCAR5

Depmap ID: ACH-001151
CCLE Name: OVCAR5_OVARY
COSMIC ID: 905969
Sanger ID: 1858
Cell Line Passport: SIDM00091
Cellosaurus RRID: CVCL_1628
Aliases: OVCAR-5
Disease
Ovarian Cancer

Disease Subtype

Adenocarcinoma, high grade serous
Lineage
Ovary

Lineage Subtype

Ovary Adenocarcinoma

Lineage Sub-subtype

High Grade Serous
Primary/Metastasis
Metastasis

OVCAR5 sequenced and profiled in following datasets

Loss-of-function screens

CRISPR (DepMap 22Q2 Public+Score, Chronos)
CRISPR (DepMap 22Q2 Public, Chronos)
CRISPR (Project Score, Chronos)
CRISPR (Project Score, CERES)

Omics Characterizations

Expression 22Q2 Public
Copy Number 22Q2 Public
Hotspot Mutations
Damaging Mutations
Other Non-conserving Mutations
Mutation 22Q2 Public
Fusion 22Q2 Public
Protein Array

Compound Viability screens

Drug sensitivity AUC (Sanger GDSC1)
Drug sensitivity AUC (Sanger GDSC2)
Drug sensitivity IC50 (Sanger GDSC1)
Drug sensitivity IC50 (Sanger GDSC2)
Drug sensitivity replicate-level dose (Sanger GDSC1)
Drug sensitivity replicate-level dose (Sanger GDSC2)
Top 10 preferentially essential genes
CRISPR (DepMap 22Q2 Public+Score, Chronos)

PGM3
ITGAV
NAMPT
CFLAR
TYMS
KRAS
CRKL
PPIL1
RBM18
FPGS


Mutation

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Fusion

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