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THP1

Depmap ID: ACH-000146
CCLE Name: THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
COSMIC ID: 909771
Sanger ID: 770
Cell Line Passport: SIDM01172
Cellosaurus RRID: CVCL_0006
Aliases: THP-1
Disease
Leukemia

Disease Subtype

Acute Myelogenous Leukemia (AML), M5 (Eosinophilic/Monocytic)
Lineage
Blood

Lineage Subtype

AML

Lineage Sub-subtype

M5
Primary/Metastasis
Primary

THP1 sequenced and profiled in following datasets


Top 10 preferentially essential genes
CRISPR (DepMap 21Q4 Public+Score, Chronos)

NRAS
ACSL4
TUBB4B
MYB
CDK6
SLC5A3
NAMPT
SETDB1
AP2S1
SCAP
RNAi (Achilles+DRIVE+Marcotte, DEMETER2)

NRAS
MYB
SPI1
A2ML1
EIF4A2
CFL1
PCNA
MED1
CDK6
MCL1



Mutation

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Translocation

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