megalencephalic leukoencephalopathy with subcortical cysts 1
Dependent Cell Lines
Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.
Dependency Score (DEMETER2)
Enriched lineages have p-values < 0.0005 shown in parentheses.
Expression & CN
Copy Number log2(relative to ploidy + 1)
CRISPR (Avana) Public 19Q3
Combined RNAi (Broad, Novartis, Marcotte)
Mutation Public 19Q3
- Official symbol: MLC1
- Full name: megalencephalic leukoencephalopathy with subcortical cysts 1
- Also known as: VL, MLC, KIAA0027, LVM
- Entrez ID: 23209
- Ensembl ID: ENSG00000100427
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