MOCS2

molybdenum cofactor synthesis 2

Dependent Cell Lines

CRISPR: 2/625

RNAi: 32/547

Dependency Score


Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.


Enriched Lineages

CRISPR

Dependency Score (CERES)

RNAi

Dependency Score (DEMETER2)

1. Solid (1.6e-09)
2. Haematopoietic And Lymphoid (1.9e-08)
3. DLBCL (2.1e-04)
4. Lymphoma (2.9e-04)


Enriched lineages have p-values < 0.0005 shown in parentheses.


Expression & CN

TPM (log2)


Copy Number log2(relative to ploidy + 1)



Top Co-dependencies

CRISPR (Avana) Public 19Q3

GenePearson correlation
PlotBROX0.26
PlotRDH110.23
PlotKLHL200.22
PlotGPX80.22
PlotKRT81-0.22

Combined RNAi (Broad, Novartis, Marcotte)

GenePearson correlation
PlotRPL7A0.34
PlotGPN20.33
PlotRPL120.31
PlotLRRC8C0.29
PlotRPS290.29

Target Tractability



Mutations

# of Cell lines



Description

Loading...  

Search external sites for MOCS2

View details


Choose dataset

Mutation Public 19Q3

Loading table...

Fusion 19Q3

Loading table...

Methylation (1kb upstream TSS) (5 52405602-52406602)

CpG Methylation

Select context(s) and press load



  • Official symbol: MOCS2
  • Full name: molybdenum cofactor synthesis 2
  • Location:
  • Also known as: MOCO1
  • Entrez ID: 4338
  • Ensembl ID: ENSG00000164172

Search external sites for MOCS2