POLR2G
RNA polymerase II subunit G
Dependent Cell Lines
CRISPR: 624/625 COMMON ESSENTIAL
RNAi: 242/547
Dependency Score
Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.
Common Essential: A gene which, in a large, pan-cancer screen, ranks in the top X most depleting genes in at least 90% of cell lines. X is chosen empirically using the minimum of the distribution of gene ranks in their 90th percentile least depleting lines.
Enriched Lineages
CRISPR
Dependency Score (CERES)
RNAi
Dependency Score (DEMETER2)
1. Lung (3.1e-04)
Enriched lineages have p-values < 0.0005 shown in parentheses.
Target Tractability
Description
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Expression Public 19Q3
Copy Number (Absolute)
Copy Number Public 19Q3
Mutation Public 19Q3
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Fusion 19Q3
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- Official symbol: POLR2G
- Full name: RNA polymerase II subunit G
- Location:
- Also known as: hRPB19, RPB7, hsRPB7
- Entrez ID: 5436
- Ensembl ID: ENSG00000168002
Search external sites for POLR2G
- PubMed ( entries)
- HUGO
- GeneCards
- Wikipedia
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- Tumor Portal
- GTEx
- COSMIC
- NCBI