RNA polymerase II subunit G
Dependent Cell Lines
CRISPR: 624/625 COMMON ESSENTIAL
Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.
Common Essential: A gene which, in a large, pan-cancer screen, ranks in the top X most depleting genes in at least 90% of cell lines. X is chosen empirically using the minimum of the distribution of gene ranks in their 90th percentile least depleting lines.
Dependency Score (DEMETER2)
Enriched lineages have p-values < 0.0005 shown in parentheses.
Expression & CN
Copy Number log2(relative to ploidy + 1)
CRISPR (Avana) Public 19Q3
Combined RNAi (Broad, Novartis, Marcotte)
Mutation Public 19Q3
- Official symbol: POLR2G
- Full name: RNA polymerase II subunit G
- Also known as: hRPB19, RPB7, hsRPB7
- Entrez ID: 5436
- Ensembl ID: ENSG00000168002
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