SPARCL1

SPARC like 1

Dependent Cell Lines

CRISPR: 0/625

RNAi: 1/547

Dependency Score


Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.


Enriched Lineages

CRISPR

Dependency Score (CERES)

RNAi

Dependency Score (DEMETER2)

1. Solid (1.3e-05)
2. Haematopoietic And Lymphoid (3.5e-04)


Enriched lineages have p-values < 0.0005 shown in parentheses.


Expression & CN

TPM (log2)


Copy Number log2(relative to ploidy + 1)



Top Co-dependencies

CRISPR (Avana) Public 19Q3

GenePearson correlation
PlotPRSS120.22
PlotAMBN0.22
PlotCXCL90.22
PlotTMEM150C0.21
PlotENOPH10.21

Combined RNAi (Broad, Novartis, Marcotte)

GenePearson correlation
PlotMORC30.43
PlotPCDHGA30.36
PlotMTPAP0.34
PlotIRF2BP10.34
PlotABHD100.34

Target Tractability



Mutations

# of Cell lines



Description

Loading...  

Search external sites for SPARCL1

View details


Choose dataset

Mutation Public 19Q3

Loading table...

Fusion 19Q3

Loading table...

Translocation

Loading table...



  • Official symbol: SPARCL1
  • Full name: SPARC like 1
  • Location:
  • Also known as: MAST9
  • Entrez ID: 8404
  • Ensembl ID: ENSG00000152583

Search external sites for SPARCL1