ZNF124

zinc finger protein 124

Dependent Cell Lines

CRISPR: 0/625

RNAi: 15/547

Dependency Score


Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.


Enriched Lineages

CRISPR

Dependency Score (CERES)

RNAi

Dependency Score (DEMETER2)

1. TPBC (3.6e-04)


Enriched lineages have p-values < 0.0005 shown in parentheses.


Expression & CN

TPM (log2)


Copy Number log2(relative to ploidy + 1)



Top Co-dependencies

CRISPR (Avana) Public 19Q3

GenePearson correlation
PlotOR2M70.38
PlotZNF6950.35
PlotOR2T270.35
PlotZNF1950.34
PlotOR2L50.30

Combined RNAi (Broad, Novartis, Marcotte)

GenePearson correlation
PlotCCDC960.29
PlotCCDC960.29
PlotUTP3-0.26
PlotZFAND10.26
PlotB3GALT4-0.26

Target Tractability



Mutations

# of Cell lines



Description

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Mutation Public 19Q3

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Fusion 19Q3

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Translocation

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  • Official symbol: ZNF124
  • Full name: zinc finger protein 124
  • Location:
  • Also known as: HZF-16, HZF16
  • Entrez ID: 7678
  • Ensembl ID: ENSG00000196418

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