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basic transcription factor 3

This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

5q13.2

GeneCards , NCBI

Executive summary

BTF3 was screened in 216 cell lines with 7 shRNAs, and 285 cell lines with 7 shRNAs.
No significant models found for BTF3

Dependency profile

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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to BTF3's dependency profile

Table genes' correlated

Correlated gene dependency	Correlation (r)	Z_score

Correlation graph for BTF3

Biomarkers for dependency on BTF3 (ATLANTIS)

Context	Dependency dataset	Biomarker types	Biomarker subset	Score transform	Top biomarker	R^2	P-Value	FDR	Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

shRNA ID	Gene Symbol	Seed1 Sequence	Seed2 Sequence	Gene Rsquared	Seed1 Rsquared	Seed2 Rsquared	Seeds Rsquared	Other Gene Rsquared	Total Rsquared	Alpha1	Alpha2	Beta	Other Gene Symbol

BTF3

Executive summary

Dependency profile

Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

Scatterplot Dependency vs Copy Number

Gene's correlated to BTF3's dependency profile

Table genes' correlated

Correlation graph for BTF3

Biomarkers for dependency on BTF3 (ATLANTIS)

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

98k shRNA library (v2.19.2)

ShRNA Quality

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