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GPR146

Description

G protein-coupled receptor 146

Summary

None

Location

7p22.3

External Links
GeneCards , NCBI

Executive summary

  • GPR146 was screened in 216 cell lines with 5 shRNAs, and 285 cell lines with 5 shRNAs.
  • No significant models found for GPR146
  • GPR146 was annotated as potentially druggable (either in DGIDB or IUPHAR/BPS Guide to PHARMACOLOGY).

Dependency profile

Histogram Table
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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to GPR146's dependency profile

Table genes' correlated

Correlated gene dependency Correlation (r) Z_score

Correlation graph for GPR146

Biomarkers for dependency on GPR146 (ATLANTIS)

Context Dependency dataset Biomarker types Biomarker subset Score transform Top biomarker R^2 P-Value FDR Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

Plot Table
shRNA ID Gene Symbol Seed1 Sequence Seed2 Sequence Gene Rsquared Seed1 Rsquared Seed2 Rsquared Seeds Rsquared Other Gene Rsquared Total Rsquared Alpha1 Alpha2 Beta Other Gene Symbol

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