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PRPF19

Description

pre-mRNA processing factor 19

Summary

PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM, Sep 2008]

Location

11q12.2

External Links
GeneCards , NCBI

Executive summary

  • PRPF19 was screened in 216 cell lines with 5 shRNAs, and 285 cell lines with 4 shRNAs.
  • No significant models found for PRPF19

Dependency profile

Histogram Table
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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to PRPF19's dependency profile

Table genes' correlated

Correlated gene dependency Correlation (r) Z_score

Correlation graph for PRPF19

Biomarkers for dependency on PRPF19 (ATLANTIS)

Context Dependency dataset Biomarker types Biomarker subset Score transform Top biomarker R^2 P-Value FDR Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

Plot Table
shRNA ID Gene Symbol Seed1 Sequence Seed2 Sequence Gene Rsquared Seed1 Rsquared Seed2 Rsquared Seeds Rsquared Other Gene Rsquared Total Rsquared Alpha1 Alpha2 Beta Other Gene Symbol

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