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RCC1

Description

regulator of chromosome condensation 1

Summary

None

Location

1p35.3

External Links
GeneCards , NCBI

Executive summary

  • RCC1 was screened in 0 cell lines with 0 shRNAs, and 285 cell lines with 8 shRNAs.
  • The search for "CYCLOPS" MDPs resulted in the most predictive model for RCC1 which had an out-of-bag R^2 of 0.11 (FDR 3.80e-02). In addition, this gene had a significant model when searching for the following MDPs: "CYCLOPS".

Dependency profile

Histogram Table
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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to RCC1's dependency profile

Table genes' correlated

Correlated gene dependency Correlation (r) Z_score

Correlation graph for RCC1

Biomarkers for dependency on RCC1 (ATLANTIS)

Context Dependency dataset Biomarker types Biomarker subset Score transform Top biomarker R^2 P-Value FDR Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

Plot Table
shRNA ID Gene Symbol Seed1 Sequence Seed2 Sequence Gene Rsquared Seed1 Rsquared Seed2 Rsquared Seeds Rsquared Other Gene Rsquared Total Rsquared Alpha1 Alpha2 Beta Other Gene Symbol

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