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unkempt family like zinc finger

This gene encodes a RING finger protein that may function in Rac signaling. It can bind to Brg/Brm-associated factor 60b and can promote its ubiquitination. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]

16p13.3

GeneCards , NCBI

Executive summary

UNKL was screened in 216 cell lines with 5 shRNAs, and 285 cell lines with 6 shRNAs.
UNKL was a six-sigma dependency in 1 cell lines.
No significant models found for UNKL

Dependency profile

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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to UNKL's dependency profile

Table genes' correlated

Correlated gene dependency	Correlation (r)	Z_score

Correlation graph for UNKL

Biomarkers for dependency on UNKL (ATLANTIS)

Context	Dependency dataset	Biomarker types	Biomarker subset	Score transform	Top biomarker	R^2	P-Value	FDR	Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

shRNA ID	Gene Symbol	Seed1 Sequence	Seed2 Sequence	Gene Rsquared	Seed1 Rsquared	Seed2 Rsquared	Seeds Rsquared	Other Gene Rsquared	Total Rsquared	Alpha1	Alpha2	Beta	Other Gene Symbol

UNKL

Executive summary

Dependency profile

Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

Scatterplot Dependency vs Copy Number

Gene's correlated to UNKL's dependency profile

Table genes' correlated

Correlation graph for UNKL

Biomarkers for dependency on UNKL (ATLANTIS)

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

98k shRNA library (v2.19.2)

ShRNA Quality

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