Welcome to the DepMap Portal
The goal of the Dependency Map (DepMap) portal is to empower the research community to make discoveries related to cancer vulnerabilities by providing open access to key cancer dependencies, analytical, and visualization tools.
Learn more about DepMap Learn more about PedDepDepMap is part of a public-private partnership called the DepMap Consortium. Learn more about becoming a member of the DepMap Consortium.
Explore the Portal
Updates and Announcements
26Q3 - Portal update
The 26Q3 release is now available! Please read the release notes for more details on new data and pipeline updates.
Release Highlights
- 150 new genome-wide CRISPR screens and Omics for adult and pediatric models, including fully integrated next-generation model data from the Neiswiender, Maffa, Brenan et al. publication.
- New Subtypes including breast cancer subtypes and PAM50 classifications are ow available to use throughout the portal.
- Updates to CRISPR pipeline including improvements in library correction, ChrY gene effect correction and removal of TKOv3 and Brunello only genes.
- Updates to Mutation dataset, GIAB/hg38 BAM patches and an updated gene list.
- New Feature! The portal now allows for generating *small multiples during Data Explorer analysis.
Read the full Release Notes
Explore More Ways To Use DepMap
Discover genetic and pharmacological dependencies
Explore MSI cancer dependency on WRN in Data ExplorerSee the Gene Dependency Overview page for Sox10
Prioritize tumor contexts and predictive biomarkers
Compare TRILACICLIB (CDK inhibitor) and RB1 expression in Data Explorer
Browse our collection of over 2000 cancer models
Dive deeper into MCF7 on our Gene Dependency page
Discover interesting targets
Find the most selective and/or predictable gene dependencies in Target discoveryContribute Cancer Models and Datasets to DepMap
