COL26A1

collagen type XXVI alpha 1 chain

Dependent Cell Lines

RNAi: 11/597

Dependency Score


Dependent Cell Line: A cell line is considered dependent if it has a probability of dependency greater than 0.5.
Dependency Score: Outcome from DEMETER2 or CERES. A lower score means that a gene is more likely to be dependent in a given cell line. A score of 0 is equivalent to a gene that is not essential whereas a score of -1 corresponds to the median of all common essential genes.


Enriched Lineages

RNAi

Dependency Score (DEMETER2)

1. Skin (4.9e-06)
2. Melanoma (6.7e-05)


Enriched lineages have p-values < 0.0005 shown in parentheses.


Expression & CN

TPM (log2)


Copy Number log2(relative to ploidy + 1)



Top Co-dependencies

Combined RNAi (Broad, Novartis, Marcotte)

GenePearson correlation
PlotPLEKHJ10.26
PlotC9orf1390.26
PlotRNF2070.25
PlotZNF2640.25
PlotKCNC20.25

Target Tractability



Description

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Fusion 19Q3

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Methylation (1kb upstream TSS) (7 101005100-101006100)

CpG Methylation

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  • Official symbol: COL26A1
  • Full name: collagen type XXVI alpha 1 chain
  • Location:
  • Also known as: Emu2, EMID2, EMI6
  • Entrez ID: 136227
  • Ensembl ID: ENSG00000160963

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