succinate dehydrogenase complex assembly factor 2


This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]



External Links
GeneCards , NCBI

Executive summary

  • SDHAF2 was screened in 0 cell lines with 0 shRNAs, and 285 cell lines with 5 shRNAs.
  • SDHAF2 was excluded from analysis due lack of differential response or no expression.
  • No significant models found for SDHAF2

Dependency profile

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Scatterplots of dependency vs Expression/Copy Number

Scatterplot Dependency vs Expression

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Scatterplot Dependency vs Copy Number

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Gene's correlated to SDHAF2's dependency profile

Table genes' correlated

Correlated gene dependency Correlation (r) Z_score

Correlation graph for SDHAF2

Biomarkers for dependency on SDHAF2 (ATLANTIS)

Context Dependency dataset Biomarker types Biomarker subset Score transform Top biomarker R^2 P-Value FDR Reports

ShRNA Hairpin level scores

55k shRNA library (v2.4.6)

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98k shRNA library (v2.19.2)

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ShRNA Quality

shRNA ID Gene Symbol Seed1 Sequence Seed2 Sequence Gene Rsquared Seed1 Rsquared Seed2 Rsquared Seeds Rsquared Other Gene Rsquared Total Rsquared Alpha1 Alpha2 Beta Other Gene Symbol